Starting at: Throughout pregnancy
Frequency: As prescribed by your health care practitioner
Purpose: To support a developing pregnancy and reduce the risk of preterm delivery in women with a history of spontaneous preterm delivery.

Progesterone supplements (usually administered as vaginal suppositories) are sometimes given in the first trimester to support implantation of the embryo and the developing pregnancy. Progesterone supplements after week 12 may also reduce the risk of preterm delivery, similar to P17 shots. Discuss with your health care practitioner whether supplemental progesterone is right for you at any point in your pregnancy.

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